Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: Incidence, risk factors and outcomes
نویسندگان
چکیده
منابع مشابه
Hepatic sinusoidal obstruction syndrome following hematopoietic stem cell transplantation.
J.m., a 43-year-old man with acute myelogenous leukemia with a monosomy 7 cytogenetic abnormality, received an allogeneic hematopoietic stem cell transplantation (HscT) from his human leukocyte antigen– matched brother. Past treatments included idarubicin and cytarabine induction therapy followed by a cycle of high-dose cytarabine. J.m. was in complete remission prior to the HscT. The condition...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Hepatic sinusoidal obstruction syndrome (SOS), previously known as veno-occlusive disease, is one of the major complications during the early period after hematopoietic cell transplantation (HCT). The disease is caused by toxic injury of conditioning therapy...
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BACKGROUND AND OBJECTIVES Survivors of pediatric hematopoietic stem cell transplantation (HSCT) are at risk for developing hypertension. The objectives of this study are to evaluate the prevalence and risk factors of early onset hypertension during the engraftment period after HSCT. SUBJECTS AND METHODS This is a retrospective study of 157 consecutive patients (mean age at HSCT: 9.1±5.1 years...
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We analyzed the factors and outcome of patients with disseminated adenovirus infection (dAdV) after allogeneic hematopoeitic stem cell transplantation (HSCT). Thirty patients with dAdV were identified among 620 allogeneic HSCT recipients. Primary diseases were leukemia (n=17), Fanconi anemia (n=12) or others (n=1). Source of stem cells was unrelated in 28 and related in 2 patients. The graft co...
متن کاملSuccessful treatment with defibrotide for sinusoidal obstruction syndrome after hematopoietic stem cell transplantation.
Sinusoidal obstruction syndrome (SOS) (formerly known as hepatic veno-occlusive disease (VOD)) is a life-threatening complication subsequent to hematopoietic stem cell transplantation. However, no completely satisfactory strategies for the treatment of SOS have been established yet. Defibrotide is a single-stranded polydeoxyribonucleotide with anti-thrombotic, anti-ischemic, anti-inflammatory a...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2015
ISSN: 0268-3369,1476-5365
DOI: 10.1038/bmt.2015.283